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Recent Advances in Ophthalmic Diseases Diagnosis using AI

Submission Deadline: 15 November 2023 (closed) View: 285

Guest Editors

Dr. Azhar Imran, Air University, Pakistan.
Prof. Jianqiang Li, Beijing University of Technology, China.
Prof. Abdulkareem Alzahrani, Al Baha University, Saudi Arabia.

Summary

Artificial intelligence (AI) has grown in popularity as it has found applications in medical diagnosis for clinical support systems. The application of artificial intelligence (AI) in ophthalmology is generating a great deal of interest in diagnosing various ophthalmic diseases that have traditionally been delicate and/or thought to be difficult to precisely diagnose by clinical experts. AI, in particular, can help ophthalmologists make accurate diagnoses by combining recently developed technologies with fundus photography, digital imaging, optical coherence tomography (OCT), and visual field examination to achieve powerful classification performance in detecting corneal and retinal anomalies.

 

These diagnostic techniques are extremely reliant on the examiner's skills and experience, resulting in substantial interobserver variations in sensitivity and specificity. The adoption of modern systems not only enables for earlier detection of eye diseases, but also allows optometrists to render more personalized treatment to their patients. A large amount of information is gathered when modern diagnostic instruments are used. Given the large number of patients, this information is challenging to assess in daily clinical practice. As a result, automated analysis of the obtained results are becoming highly significant. Ophthalmologists now have access to a diverse range of medications and medical devices that have transformed the treatment of both common and rare eye diseases. This allows patients to receive possible treatment in terms of functional outcomes and safety.


Keywords

Retinal Disease Detection
Diagnostic imaging
Cataract, Glaucoma, Diabetic Retinopathy Detection and Grading
Fundus Image Classification
Detection of Visual Diseases from Medical Images
Optical Diagnosis
Artificial Intelligence
Molecular Pathology
Identification and Classification of Ophthalmic Diseases
Biomarkers
Treatment Options

Published Papers


  • Open Access

    ARTICLE

    An Implementation of Multiscale Line Detection and Mathematical Morphology for Efficient and Precise Blood Vessel Segmentation in Fundus Images

    Syed Ayaz Ali Shah, Aamir Shahzad, Musaed Alhussein, Chuan Meng Goh, Khursheed Aurangzeb, Tong Boon Tang, Muhammad Awais
    CMC-Computers, Materials & Continua, Vol.79, No.2, pp. 2565-2583, 2024, DOI:10.32604/cmc.2024.047597
    (This article belongs to the Special Issue: Recent Advances in Ophthalmic Diseases Diagnosis using AI)
    Abstract Diagnosing various diseases such as glaucoma, age-related macular degeneration, cardiovascular conditions, and diabetic retinopathy involves segmenting retinal blood vessels. The task is particularly challenging when dealing with color fundus images due to issues like non-uniform illumination, low contrast, and variations in vessel appearance, especially in the presence of different pathologies. Furthermore, the speed of the retinal vessel segmentation system is of utmost importance. With the surge of now available big data, the speed of the algorithm becomes increasingly important, carrying almost equivalent weightage to the accuracy of the algorithm. To address these challenges, we present… More >

    Graphic Abstract

    An Implementation of Multiscale Line Detection and Mathematical Morphology for Efficient and Precise Blood Vessel Segmentation in Fundus Images

  • Open Access

    ARTICLE

    ProNet Adaptive Retinal Vessel Segmentation Algorithm Based on Improved UperNet Network

    Sijia Zhu, Pinxiu Wang, Ke Shen
    CMC-Computers, Materials & Continua, Vol.78, No.1, pp. 283-302, 2024, DOI:10.32604/cmc.2023.045506
    (This article belongs to the Special Issue: Recent Advances in Ophthalmic Diseases Diagnosis using AI)
    Abstract This paper proposes a new network structure, namely the ProNet network. Retinal medical image segmentation can help clinical diagnosis of related eye diseases and is essential for subsequent rational treatment. The baseline model of the ProNet network is UperNet (Unified perceptual parsing Network), and the backbone network is ConvNext (Convolutional Network). A network structure based on depth-separable convolution and 1 × 1 convolution is used, which has good performance and robustness. We further optimise ProNet mainly in two aspects. One is data enhancement using increased noise and slight angle rotation, which can significantly increase the… More >

  • Open Access

    ARTICLE

    Optimizing Fully Convolutional Encoder-Decoder Network for Segmentation of Diabetic Eye Disease

    Abdul Qadir Khan, Guangmin Sun, Yu Li, Anas Bilal, Malik Abdul Manan
    CMC-Computers, Materials & Continua, Vol.77, No.2, pp. 2481-2504, 2023, DOI:10.32604/cmc.2023.043239
    (This article belongs to the Special Issue: Recent Advances in Ophthalmic Diseases Diagnosis using AI)
    Abstract In the emerging field of image segmentation, Fully Convolutional Networks (FCNs) have recently become prominent. However, their effectiveness is intimately linked with the correct selection and fine-tuning of hyperparameters, which can often be a cumbersome manual task. The main aim of this study is to propose a more efficient, less labour-intensive approach to hyperparameter optimization in FCNs for segmenting fundus images. To this end, our research introduces a hyperparameter-optimized Fully Convolutional Encoder-Decoder Network (FCEDN). The optimization is handled by a novel Genetic Grey Wolf Optimization (G-GWO) algorithm. This algorithm employs the Genetic Algorithm (GA) to… More >

  • Open Access

    ARTICLE

    DT-Net: Joint Dual-Input Transformer and CNN for Retinal Vessel Segmentation

    Wenran Jia, Simin Ma, Peng Geng, Yan Sun
    CMC-Computers, Materials & Continua, Vol.76, No.3, pp. 3393-3411, 2023, DOI:10.32604/cmc.2023.040091
    (This article belongs to the Special Issue: Recent Advances in Ophthalmic Diseases Diagnosis using AI)
    Abstract Retinal vessel segmentation in fundus images plays an essential role in the screening, diagnosis, and treatment of many diseases. The acquired fundus images generally have the following problems: uneven illumination, high noise, and complex structure. It makes vessel segmentation very challenging. Previous methods of retinal vascular segmentation mainly use convolutional neural networks on U Network (U-Net) models, and they have many limitations and shortcomings, such as the loss of microvascular details at the end of the vessels. We address the limitations of convolution by introducing the transformer into retinal vessel segmentation. Therefore, we propose a… More >

  • Open Access

    ARTICLE

    Deep Learning with a Novel Concoction Loss Function for Identification of Ophthalmic Disease

    Sayyid Kamran Hussain, Ali Haider Khan, Malek Alrashidi, Sajid Iqbal, Qazi Mudassar Ilyas, Kamran Shah
    CMC-Computers, Materials & Continua, Vol.76, No.3, pp. 3763-3781, 2023, DOI:10.32604/cmc.2023.041722
    (This article belongs to the Special Issue: Recent Advances in Ophthalmic Diseases Diagnosis using AI)
    Abstract As ocular computer-aided diagnostic (CAD) tools become more widely accessible, many researchers are developing deep learning (DL) methods to aid in ocular disease (OHD) diagnosis. Common eye diseases like cataracts (CATR), glaucoma (GLU), and age-related macular degeneration (AMD) are the focus of this study, which uses DL to examine their identification. Data imbalance and outliers are widespread in fundus images, which can make it difficult to apply many DL algorithms to accomplish this analytical assignment. The creation of effcient and reliable DL algorithms is seen to be the key to further enhancing detection performance. Using… More >

  • Open Access

    ARTICLE

    PLDMLT: Multi-Task Learning of Diabetic Retinopathy Using the Pixel-Level Labeled Fundus Images

    Hengyang Liu, Chuncheng Huang
    CMC-Computers, Materials & Continua, Vol.76, No.2, pp. 1745-1761, 2023, DOI:10.32604/cmc.2023.040710
    (This article belongs to the Special Issue: Recent Advances in Ophthalmic Diseases Diagnosis using AI)
    Abstract In the field of medical images, pixel-level labels are time-consuming and expensive to acquire, while image-level labels are relatively easier to obtain. Therefore, it makes sense to learn more information (knowledge) from a small number of hard-to-get pixel-level annotated images to apply to different tasks to maximize their usefulness and save time and training costs. In this paper, using Pixel-Level Labeled Images for Multi-Task Learning (PLDMLT), we focus on grading the severity of fundus images for Diabetic Retinopathy (DR). This is because, for the segmentation task, there is a finely labeled mask, while the severity… More >

  • Open Access

    ARTICLE

    Enhanced Nature Inspired-Support Vector Machine for Glaucoma Detection

    Jahanzaib Latif, Shanshan Tu, Chuangbai Xiao, Anas Bilal, Sadaqat Ur Rehman, Zohaib Ahmad
    CMC-Computers, Materials & Continua, Vol.76, No.1, pp. 1151-1172, 2023, DOI:10.32604/cmc.2023.040152
    (This article belongs to the Special Issue: Recent Advances in Ophthalmic Diseases Diagnosis using AI)
    Abstract Glaucoma is a progressive eye disease that can lead to blindness if left untreated. Early detection is crucial to prevent vision loss, but current manual scanning methods are expensive, time-consuming, and require specialized expertise. This study presents a novel approach to Glaucoma detection using the Enhanced Grey Wolf Optimized Support Vector Machine (EGWO-SVM) method. The proposed method involves preprocessing steps such as removing image noise using the adaptive median filter (AMF) and feature extraction using the previously processed speeded-up robust feature (SURF), histogram of oriented gradients (HOG), and Global features. The enhanced Grey Wolf Optimization More >

  • Open Access

    ARTICLE

    Spatial Correlation Module for Classification of Multi-Label Ocular Diseases Using Color Fundus Images

    Ali Haider Khan, Hassaan Malik, Wajeeha Khalil, Sayyid Kamran Hussain, Tayyaba Anees, Muzammil Hussain
    CMC-Computers, Materials & Continua, Vol.76, No.1, pp. 133-150, 2023, DOI:10.32604/cmc.2023.039518
    (This article belongs to the Special Issue: Recent Advances in Ophthalmic Diseases Diagnosis using AI)
    Abstract To prevent irreversible damage to one’s eyesight, ocular diseases (ODs) need to be recognized and treated immediately. Color fundus imaging (CFI) is a screening technology that is both effective and economical. According to CFIs, the early stages of the disease are characterized by a paucity of observable symptoms, which necessitates the prompt creation of automated and robust diagnostic algorithms. The traditional research focuses on image-level diagnostics that attend to the left and right eyes in isolation without making use of pertinent correlation data between the two sets of eyes. In addition, they usually only target… More >

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